VASCULOGENESIS KIT
GROWING BLOOD VESSELS
JUST GOT EASIER
3D microvascular networks (MVNs) are key building blocks for dynamic disease models & predictive drug testing.
Why are MVNs essential to preclinical models?
MVNs create dynamic, perfusable microenvironments that mimic human biology, enabling realistic cellular interactions, biomechanical cues, and drug responsiveness. By supporting the development of 3D functional tissues, MVNs enhance drug transport and permeability studies—critical for vascular diseases, cancer, and regenerative medicine.
What limits widespread adoption?
Achieving scalable and consistent MVN formation in an affordable and standardized platform remains a challenge.
AIM’s solution: VasQ Kit
The all-in-one kit to generate perfusable 3D MVNs
Key Features
- Realistic. Self-assembled vasculature that mimics human tissue.
- Fast. Perfusable 3D MVNs achieved within 1 week.
- Streamlined. No pumps or plate rockers required.
- Automated. Compatible with automated imaging & liquid handling.
- Reproducible. Standardized cell sources ensure consistency and overcome lot-to-lot variability.
- Translatable. Easily integrate organoids, spheroids or tissues with the vascular network
What's Included?
MPS Platform
AIM Biotech’s organiX Plate
Standardized Cells
Human endothelial cells & lung fibroblasts
Extracellular Matrix
Pre-qualified fibrinogen & thrombin
Supplements
VEGF & G418
Product Details
- Organoid, spheroid and tissue integration. Compatible with a wide range of organoids and spheroids for vascularized 3D culture and functional assays.
- All-in-one solution. VasQ Kit streamlines the generation of MVNs, enabling researchers to create, test, and analyze human-relevant vascular biology.
- Standardized cell sources. The kit includes hTERT-immortalized Human Umbilical Vein Endothelial Cells (HUVECs) and lung fibroblasts (LFs) that retain primary cell phenotype while ensuring long-term usability for consistent results. Learn more about the advantages of hTERT-immortalized cell sources here and review a comparative study here.
- Next-level reproducibility. Our team ensures quality in every product, providing researchers with consistent blood vessel formation.
- Self-assembled vasculature. Endothelial cells co-cultured with lung fibroblasts in fibrin gels self-assemble into 3D MVNs, mimicking the process of vasculogenesis in vivo and establishing realistic cell-cell and cell-ECM interactions.
Product Validation
Click images for detail
Selected Publications Using AIM’s Technology
Oncology Applications
- In Vitro integration of a functional vasculature to model endothelial regulation of chemotherapy and T-cell immunotherapy in liver cancer. Vasudevan, J., Vijayakumar, R., Reales-Calderon, J. A., Lam, M. S., Ow, J. R., Aw, J., ... & Pavesi, A. (2025). Biomaterials, 320, 123175.
For more publications using our technology to study vascular biology, visit our website publications page.
