Applications

Applications

Run simple assays or create complex biological models

T Cell Efficiency Assay

T Cell Efficiency Assay

Functional assay for determining the killing efficiency of engineered T cells.

Immunotherapy

Immunotherapy

Ex vivo model recapitulating the immune checkpoint response, with tissue from syngeneic mice, PDX and clinical biopsies.

Metastasis Assays

Metastasis Assays

Intravasation & extravasation assays, together with spheroid dispersion assays, model the key steps in metastasis.

Cell Migration

Cell Migration

Cell migration/invasion assay that offers an unambiguous starting line, real-time imaging and the ability to engineer the microenvironment being invaded.

Vasculogenesis

Vasculogenesis

Perfusable microvascular networks to model target organs for metastasis assays, and for vascularising tutors/organoids.

Angiogenesis

Angiogenesis

Angiogenesis model for research and drug development.

Spheriod Dispersion

Spheriod Dispersion

Tumor spheroids co-cultured with endothelial cells model the epithelial-mesenchymal transition in cancer.

Blood Brain Barrier

Blood Brain Barrier

Blood-brain barrier model comprising all-human cell triculture shows permeability level similar to in vivo models.

Protocols

et|icon_genius|

General Protocols

  • Learn the basics of using 3D cell culture chips and accessories.
  • These building blocks enable users to design their own organotypic models.
fas|fa-file-medical-alt|

Application-Specific Protocols

  • Use AIM chips & accessories to investigate vascular functions, cancer, neural guidance and stem cell differentiation.
  • Develop new models with your own combinations of cells and culture conditions.