The emergence of organoids for in vitro cancer research and drug development opens the door for new ways to assay tumor and tissue evolution and pharmacological responses. This is especially true as advances in real-time live cell imaging and new automated analytics like Digital Spatial Profiling become more widely leveraged.

While standard 2D tissue culture plates are convenient, they limit organoid research to free floating suspensions that lack experimental flexibility and more importantly prevent the creation of meaningful surrounding tissue context for the organoid, similar to studying the organoid in isolation.

organiX is an easy-to-use 3D tissue culture platform that uses a modified version of AIM Biotech’s BioAvatar-enabling microfluidic technology, specifically adapted to handle the requirements of larger tissues.

Now, you can easily recreate the complexities of the human tissue microenvironment, resulting in more meaningful, human data for preclinical drug discovery and functional precision medicine approaches.

Culture – biopsies, organoids, tumor tumoroids, spheroids or any cell/tissue aggregate up to 2 mm in diameter

Contextualize – set assay conditions with perfusable vasculature, co-culture, signaling gradients and media flow for an in vivo-like tumor microenvironment (TME)

Extract – First, obtain real time high resolution imaging data and then easily extract tissue samples for downstream analysis