Features

• 24 independent experiments on a single organiX Plate
• Same configuration of gel region and flanking media channels as the proven idenTx platform, optimized for large tissue samples up to 2mm in diameter
• Easily extract intact tissue samples for histology
• Integrated media wells at each end of media channels, 300uL each
• Compliance with SBS/ANSI 384-well plate standard
• Gas permeable laminate for effective gas exchange​​
• Excellent optical clarity
• Sterile & ready-to-use

Benefits

• Easy scale-up of experiments and assays with up to 24 wells
• Compatible with laboratory automation / robotic fluid handling
• Compatible with a wide range of imaging modalities
• Compatible with next generation analytical techniques like Digital Spatial Profiling
• Establish physiological fluid flow and chemical gradients
• Compatible with all polymerizable gels
• Enables monotypic or organotypic co-culture models
• Designed for rapid media exchange through vacuum aspiration with no risk of over-aspiration

organiX is a revolution in Human 3D Tissue Culture.

Designed to enable drug discovery and targeted therapies in large tissue samples like biopsies, organoids, tumoroids, spheroids and tissue aggregates, organiX allows for the detailed recreation of tissue and tumor microenvironments that is missing from current organoid research.

While standard 2D tissue culture plates are convenient, they limit organoid research to free floating suspensions that lack experimental flexibility and more importantly prevent the creation of meaningful surrounding tissue context for the organoid, similar to studying the organoid in isolation.

The ability to create actual physiological context for the study of these larger tissue samples is what sets organiX apart.

organiX is an easy-to-use 3D tissue culture platform that uses a modified version of AIM Biotech’s BioAvatar-enabling microfluidic technology, specifically adapted to handle the requirements of larger tissues.

Now, you can easily recreate the complexities of the human tissue microenvironment, resulting in more meaningful, human data for preclinical drug discovery and functional precision medicine approaches.

• organiX Handling Protocol