Human Data Can’t Wait for Clinical Trials.

3D HUMAN BIOLOGY-ON-A-CHIP FOR HUMANIZED DRUG DISCOVERY AND CLINICAL DECISION MAKING

Accelerating drug discovery with AIM Biotech’s humanized BioAvatar products & services.

From the most demanding basic research, to predictive screens for drug discovery, to the tailored selection of precision medicines, AIM Biotech enables and accelerates the development of cutting-edge therapeutics. This is made possible through AIM Biotech’s BioAvatar technology, which embodies our core expertise in the design and manufacture of sophisticated microfluidic systems and human tissue models. Our BioAvatars combine unmatched recapitulation of human biology with unparalleled ease-of-use, resulting in a powerful solution to move medicine forward.

BioAvatars enable:

Humanized pre-clinical insights

Humanized pre-clinical insights for increased predictability of clinical outcomes

drug discovery process

Acceleration of the drug discovery process through easy-to-implement humanized organ-on-a-chip models

Replacement of animal models

Replacement of animal models in pre-clinical trials

Explore AIM Biotech Solutions for Humanized Drug Discovery and Functional Precision Medicine

Introducing organiX: specifically made for Organoids and Biopsies

organiX is a revolution in Human Tissue and Biopsy Culture for Functional Precision Medicine and Drug Discovery

Designed to enable drug discovery and targeted therapies in large tissue samples like biopsies, organoids, tumoroids, spheroids and tissue aggregates, organiX allows for the detailed recreation of tissue and tumor microenvironments that is missing from current organoid research.

The ability to create actual physiological context for the study of these larger tissue samples is what sets organiX apart.

organiX Plate - Human Tissue | Translated.

organiX Plate

Amplify the power of organoid research and biopsy characterization with organiX

Culture

Culture – biopsies, organoids, tumor tumoroids, spheroids or any cell/tissue aggregate up to 2 mm in diameter

Contextualize

Contextualize – set assay conditions with perfusable vasculature, co-culture, signaling gradients and media flow for an in vivo-like tumor microenvironment (TME)

Extract

Extract – First, obtain real time high resolution imaging data and then easily extract tissue samples for downstream analysis

Level Up

Level Up! – Now revolutionize your fully contextualized organoid research utilizing conventional immunohistochemistry and next generation technologies like Digital Spatial Profiling

Your study. Our lab. Human data.

Contract research services for humanized, organ-on-a-chip studies

With AIM Biotech contract research services, increasing throughput while maintaining assay sophistication is our expertise. Our pharma-focused solutions combine speed and simplicity with the ability to model complex tissues that you expect from organ-on-a-chip assays.

Let AIM Biotech accelerate your drug discovery programs using our humanized BioAvatar Technology in our state-of-the-art research services lab. Our team can even work with you to design, develop, and execute custom assays to deliver human-focused, clinically-relevant results that move your drug discovery programs forward.

Custom assay development

Custom assay development

Custom assay development

Rapid humanized throughput

Functional immuno-oncology assays

Functional immuno-oncology assays

Answer primary research questions

Answer primary research questions

Data on routine screens

Data on routine screens

In-vitro organ models

In-vitro organ models

Your path to predictive data and insightful diagnostics.

Products

Simple-to-use, fully scalable microfluidic systems in plate and chip formats to recapitulate human physiology.

Assays

Assays

Validated protocols in T-cell efficiency, immunotherapies, cell migration, vasculogenesis and more

services

Services

Custom assay development and higher-throughput, high-content screening with assays of  your choice

Reportable’s software and service helps companies be heard and make sense of what’s being said.

Research

Feasibility studies
Drug/target ID
Mechanism of action
Assay development

Drug Discovery

In vitro screening
Lead optimization
ADME toxicity studies
Safety pharmacology

Diagnostics

Biomarkers
Cohort selection
Personal/targeted Tx
Clinical avatar

Building a functional human vascular disease model using AIM Biotech 3D cell culture technology

Building a functional human vascular disease model using AIM Biotech 3D cell culture technology

Understanding the interactions between endothelial cells and vascular smooth muscle cells is critical for the study of vascular disease.  Yet, there are few existing models which can simply and reliably recapitulate the cellular crosstalk in human microvascular networks. However, in a recent...

Immunotherapy month: T-cells and transplants—avoiding cancer relapse after liver transplantation using AIM Biotech’s organ-on-a-chip assays

Immunotherapy month: T-cells and transplants—avoiding cancer relapse after liver transplantation using AIM Biotech’s organ-on-a-chip assays

To round out our month-long series highlighting research on adoptive T cell immunotherapy, today we’ll take a look at how scientists are modifying T cells to help prevent cancer relapse on liver transplanted patients, harnessing AIM Biotech’s technology. In cases where a liver tumor can’t be...

Immunotherapy month: Receptor conflict—keeping cancer-killing T cells on-target using AIM Biotech’s organ-on-a-chip assays

Immunotherapy month: Receptor conflict—keeping cancer-killing T cells on-target using AIM Biotech’s organ-on-a-chip assays

This month on AIM’s Voices feed is dedicated to the fascinating research being done on adoptive T cell immunotherapy. Today, we’ll take a look at how scientists used AIM Biotech’s organ-on-a-chip technology to build on previous studies and refine this promising new technique to potentially...