Human Data Can’t Wait for Clinical Trials.
3D HUMAN BIOLOGY-ON-A-CHIP FOR HUMANIZED DRUG DISCOVERY AND CLINICAL DECISION MAKING
Accelerating drug discovery with AIM Biotech’s humanized BioAvatar products & services.
From the most demanding basic research, to predictive screens for drug discovery, to the tailored selection of precision medicines, AIM Biotech enables and accelerates the development of cutting-edge therapeutics. This is made possible through AIM Biotech’s BioAvatar technology, which embodies our core expertise in the design and manufacture of sophisticated microfluidic systems and human tissue models. Our BioAvatars combine unmatched recapitulation of human biology with unparalleled ease-of-use, resulting in a powerful solution to move medicine forward.
Humanized pre-clinical insights for increased predictability of clinical outcomes
Acceleration of the drug discovery process through easy-to-implement humanized organ-on-a-chip models
Replacement of animal models in pre-clinical trials
Explore AIM Biotech Solutions for Humanized Drug Discovery and Functional Precision Medicine
organiX Plate - Human Tissue | Translated.
Amplify the power of organoid research and biopsy characterization with organiX
Culture – biopsies, organoids, tumor tumoroids, spheroids or any cell/tissue aggregate up to 2 mm in diameter
Contextualize – set assay conditions with perfusable vasculature, co-culture, signaling gradients and media flow for an in vivo-like tumor microenvironment (TME)
Extract – First, obtain real time high resolution imaging data and then easily extract tissue samples for downstream analysis
Level Up! – Now revolutionize your fully contextualized organoid research utilizing conventional immunohistochemistry and next generation technologies like Digital Spatial Profiling
Human biology-on-a-chip. Simplified.
AIM Biotech’s proven 3D Cell Culture Chip, DAX-1
This is AIM Biotech’s proven 3D Cell Culture Chip, now part of the idenTx family. Designed in a microscope slide format, this most basic component of the idenTx family enables 3 simultaneous experiments. It is ideal for establishing experimental feasibility or for general low-throughput applications.
Human biology-on-a-chip. Standardized.
idenTx 9 Plate
Three fully-integrated idenTx 3 Chips enable 9 simultaneous experiments; scale up for introduction of plate-based robotics and automation.
Human biology-on-a-chip. Multiplied.
idenTx 40 Plate
Highest throughput plate option, enabling 40 simultaneous experiments to fully accelerate drug discovery through high-content screening.
Human Data. Experimental Simplicity.
Scalability without Compromise.
Unmatched ease-of-use: no special handling, no special training, no special hardware
Built in Scalability to take your research from feasibility to higher throughput screening
Your study. Our lab. Human data.
Contract research services for humanized, organ-on-a-chip studies
With AIM Biotech contract research services, increasing throughput while maintaining assay sophistication is our expertise. Our pharma-focused solutions combine speed and simplicity with the ability to model complex tissues that you expect from organ-on-a-chip assays.
Let AIM Biotech accelerate your drug discovery programs using our humanized BioAvatar Technology in our state-of-the-art research services lab. Our team can even work with you to design, develop, and execute custom assays to deliver human-focused, clinically-relevant results that move your drug discovery programs forward.
Custom assay development
Rapid humanized throughput
Functional immuno-oncology assays
Answer primary research questions
Data on routine screens
In-vitro organ models
For today’s post in our immune checkpoint series, we’ll discuss work published in Cell in 2018 by Sade-Feldman et al., and how they leveraged the economy of cost from AIM’s idenTx organ-on-a-chip assays to turn what would have been a six-variable animal study into a comparatively simple in...
Having a human cell-based model that mimics the in vivo tumor microenvironment and cell-to-cell interactions is invaluable for studying new cancer therapies. In our last post, we talked about growing spheroids using our idenTx family of 3D tissue culture chips and plates to reproduce in vivo...
One of the major challenges in developing successful cancer therapies is the inhibitory effect caused by immune checkpoint resistance, normally including the PD-1 checkpoint protein in T cells that we’ve highlighted in previous posts. As a result, in vitro models that faithfully recreate the...