Non-Animal Preclinical Models for Precision Human Clinical Insights
3D HUMAN BIOLOGY-ON-A-CHIP FOR HUMANIZED DRUG DISCOVERY AND CLINICAL DECISION MAKING
AIM Biotech is leading the shift from preclinical animal models to humanized in vitro physiological models for the discovery of new medicines.
Researchers and regulators around the globe know that when it comes to predicting drug efficacy, animal models too often lead us down the wrong path. That is why they are demanding non-animal, in vitro models for drug discovery research.
AIM Biotech is answering the call with our idenTx and organiX humanized 3D microfluidic platforms. These systems combine unmatched recapitulation of human biology with unparalleled ease-of-use, resulting in a powerful solution to move medicine forward.
From our simple-to-use microfluidic platforms to our full service contract research offerings for Cancer, Immuno-oncology, Vascular Biology and Neurobiology, AIM Biotech is leading the non-animal drug discovery revolution.
Explore AIM Biotech Solutions for Humanized Drug Discovery and Functional Precision Medicine
organiX Plate - Human Tissue | Translated.
Amplify the power of organoid research and biopsy characterization with organiX
Culture – biopsies, organoids, tumor tumoroids, spheroids or any cell/tissue aggregate up to 2 mm in diameter
Contextualize – set assay conditions with perfusable vasculature, co-culture, signaling gradients and media flow for an in vivo-like tumor microenvironment (TME)
Extract – First, obtain real time high resolution imaging data and then easily extract tissue samples for downstream analysis
Level Up! – Now revolutionize your fully contextualized organoid research utilizing conventional immunohistochemistry and next generation technologies like Digital Spatial Profiling
Human biology-on-a-chip. Simplified.
AIM Biotech’s proven 3D Cell Culture Chip, DAX-1
This is AIM Biotech’s proven 3D Cell Culture Chip, now part of the idenTx family. Designed in a microscope slide format, this most basic component of the idenTx family enables 3 simultaneous experiments. It is ideal for establishing experimental feasibility or for general low-throughput applications.
Human biology-on-a-chip. Standardized.
idenTx 9 Plate
Three fully-integrated idenTx 3 Chips enable 9 simultaneous experiments; scale up for introduction of plate-based robotics and automation.
Human biology-on-a-chip. Multiplied.
idenTx 40 Plate
Highest throughput plate option, enabling 40 simultaneous experiments to fully accelerate drug discovery through high-content screening.
Human Data. Experimental Simplicity.
Scalability without Compromise.
Unmatched ease-of-use: no special handling, no special training, no special hardware
Built in Scalability to take your research from feasibility to higher throughput screening
Your study. Our lab. Human data.
Contract research services for humanized, organ-on-a-chip studies
With AIM Biotech contract research services, increasing throughput while maintaining assay sophistication is our expertise. Our pharma-focused solutions combine speed and simplicity with the ability to model complex tissues that you expect from organ-on-a-chip assays.
Let AIM Biotech accelerate your drug discovery programs using our humanized BioAvatar Technology in our state-of-the-art research services lab. Our team can even work with you to design, develop, and execute custom assays to deliver human-focused, clinically-relevant results that move your drug discovery programs forward.
Custom assay development
Rapid humanized throughput
Functional immuno-oncology assays
Answer primary research questions
Data on routine screens
In vitro organ models
AIM Biotech partners with Nikon to provide organ-on-a-chip imaging and analysis contract services for drug discovery
Nikon Corporation announced on Wednesday that AIM Biotech is one of the select organ-on-a-chip (OOAC) providers to support Nikon’s expanding global contract research services for drug discovery. This partnership is a result of collaborative efforts between Nikon and AIM Biotech to demonstrate...
AIM Biotech is using Opentrons's OT-2 lab robot to implement automated drug discovery on in vitro platforms that provide more predictive data and higher throughput.
In this last article of the immune checkpoint series, we discuss how scientists used AIM Biotech’s Avatar technology to study when, how, and which cells express the PD-L1 immune protein in breast cancer. PD-L1 expression promotes tumor growth by offering an invasive behaviour to cancer cells....