Understanding PD-L1 expression in breast cancer with the idenTx chip

Understanding PD-L1 expression in breast cancer with the idenTx chip

In this last article of the immune checkpoint series, we discuss how scientists used AIM Biotech’s Avatar technology to study when, how, and which cells express the PD-L1 immune protein in breast cancer. PD-L1 expression promotes tumor growth by offering an invasive...
Step-by-step: Data and insights from a human cancer-on-a-chip model

Step-by-step: Data and insights from a human cancer-on-a-chip model

Having a human cell-based model that mimics the in vivo tumor microenvironment and cell-to-cell interactions is invaluable for studying new cancer therapies. In our last post, we talked about growing spheroids using our idenTx family of 3D tissue culture chips and...
Modeling immune checkpoint blockade using idenTx

Modeling immune checkpoint blockade using idenTx

One of the major challenges in developing successful cancer therapies is the inhibitory effect caused by immune checkpoint resistance, normally including the PD-1 checkpoint protein in T cells that we’ve highlighted in previous posts. As a result, in vitro models that...